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Previous studies have implicated specific fatty acids and elevated MUFA-to-PUFA (monounsaturated fatty acids to polyunsaturated fatty acids) ratio in lifespan modulation 31,32,33

This elegant shuttle system serves dual purposes: enabling fatty acid oxidation while preventing excess acyl-CoA accumulation in the cytosol and mitochondrial matrix

However, because weight loss can change your requirement for thyroid hormone (Levothyroxine), it is important to monitor your thyroid levels closely with your GP and be prepared to adjust your dosage if necessary