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The special feature noted in the present study could be responsible, in particular, for the increased expression and internalization of VEGFR2, which is known to be essential for endothelial function, and the activation of the VEGFR2-Akt-eNOS signaling pathway[25]

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Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

That being said, a little understanding of the relationship between glutathione, water, and detoxification will shed some common sense light on this suggestion