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Anti-Inflammatory Properties Chronic inflammation is linked to many health problems, including heart disease, arthritis, and autoimmune disorders

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The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4

For researchers submitting protocols for institutional review or documenting rationale for compound selection, the Matrixyl vs GHK-Cu evidence gap is worth noting