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In the multivariable Cox proportional hazard regression model adjusted for sex, age, marital status, duration of diabetes, hemoglobin A1c, estimated glomerular filtration rate, cardiovascular disease, use of insulin, use of cholesterol lowering medicine, and use of blood pressure lowering medicine, exposure to once-weekly semaglutide also was independently associated with a higher risk of upcoming NAION (HR 219, 95% CI 154 312)

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If you are struggling to meet your nutritional needs, experiencing unintended muscle loss, or finding it difficult to manage side effects, consult your GP or ask for a referral to a registered dietitian