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Longitudinal analyses from the Phase 2 and Phase 3 trials show that the incidence of new-onset nausea and vomiting peaked during the first 4-8 weeks of treatment and then declined substantially during the maintenance phase

However, there was a study conducted with a randomized, double-blind, placebo-controlled design and a 6-month follow-up found that statins are related with glucose metabolism impairment, which can increase the risk of type 2 diabetes mellitus

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To mitigate these economic impacts, management should prioritize prevention and inoculum reduction through an integrated strategy: deployment of tolerant/resistant cultivars where available (e.g., Behbahan and Dashtestan in affected areas of Iran