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Multicenter trials would provide sufficient power to detect clinically meaningful effects and assess safety across diverse patient populations

Diaz-Ruano AB, Gomez-Jimenez E, Llamas-Jimenez G, Ramirez-Muoz A, Espejo-Hijano P, Rubio-Navarro A, et al

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"6PPD-Q may contribute to AD pathogenesis, potentially through inducing oxidative stress, activating neuroinflammation, and disrupting kinase signaling networks." 6PPD-Q toxins are caused by a reaction of microscopic rubber particles, shed from tires, that react with ozone in the atmosphere