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Drugs such as cocaine and nicotine lead to a much larger surge of dopamine, which strongly reinforces the link between consuming the drug and the pleasure that results

Expect an adjustment period as you titrate to semaglutides maintenance dose, with full additional benefit becoming apparent over several months

doi: 10.3389/fendo.2024.1431292

Risks and Considerations for Endurance Athletes Using GLP-1 RAs If a triathlete or endurance athlete is on (or planning to take) a GLP-1 receptor agonist medication, there are several key considerations and potential risks to keep in mind