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The results were as follows: Weekly tirzepatide 5 mg: -15.0% weight reduction from baseline weight Weekly tirzepatide 10 mg: -19.5% weight reduction from baseline weight Weekly tirzepatide 15 mg: -20.9% weight reduction from baseline weight Placebo: -3.1% weight reduction from baseline weight Note: Even body weight reductions of 5-10% from baseline body weight in obese or overweight individuals can result in big benefits, including improvements in systolic blood pressure and diastolic blood pressure, cholesterol, and blood sugar

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The maximum dose is 12.5 mg/1,000 mg (empagliflozin / metformin) twice daily Synjardy XR Adults only: The typical starting dose is 10 mg/1000 mg (empagliflozin / metformin) by mouth once daily in the morning with food