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These include antibiotics (especially penicillins and sulfa drugs), nonsteroidal anti-inflammatory drugs (NSAIDs), and antiseizure drugs
Studies show this combination can improve pain control, particularly after surgery, without significantly increasing side effects when each drug stays within recommended limits
Klutstein M, Nejman D, Greenfield R, Cedar H
Since IL-17 receptor A (IL-17RA) has been shown to mediate communication from the meninges to the cortex 47 , we next examined whether the beneficial effect of peripherally targeting CD38 could be mediated in part through modulation of cortical IL-17RA and IL-1 signaling, which we observed to drive T H 17 pathogenicity
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