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Overview of Clinical Trial Study 1 (NCT03574597) was a multi-national, multi-center, placebo-controlled, double-blind trial to determine the effect of WEGOVY injection relative to placebo on major adverse CV events (MACE) when added to current standard of care, which included management of CV risk factors and individualized healthy lifestyle counseling (including diet and physical activity) in adults with established CV disease and either obesity or overweight

For patients who respond better to a pure GLP-1 agonist without the GIP receptor activity that tirzepatide adds, semaglutide may actually be the better choice