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Description

based on consistent formation of -helical structure in initial rounds of structure calculations in which no hydrogen bond restraints were defined)

Mushenkova NV, Bezsonov EE, Orekhova VA, Popkova TV, Starodubova AV, Orekhov AN

Bioorg Med Chem Lett 25:40574064 Kazda CM, Ding Y, Kelly RP et al (2016) Evaluation of efficacy and safety of the glucagon receptor antagonist LY2409021 in patients with type 2 diabetes: 12- and 24-week phase 2 studies