Conclusion: AOD 9604 significantly improves bone density and bone mass in elderly osteoporotic rats, while promoting bone formation and inhibiting bone resorption, with better effects than bisphosphonates that simply inhibit bone resorption
The goal is not to eliminate exercise-induced oxidative stress entirely, which would potentially impair training adaptations, but to ensure that antioxidant defenses remain adequate to prevent excessive cellular damage while allowing beneficial adaptive signaling to occur
Regular injections can provide sustained benefits
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