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Additional TRIUMPH and Other Phase 3 Trials Lilly has initiated or announced additional Phase 3 trials for retatrutide: Chronic low back pain -- Phase 3 initiated in Q3 2025 Overweight/obesity (additional) -- new Phase 3 trial initiated in Q3 2025 MASLD master protocol (NCT07165028) -- a Phase 3 multi-agent master protocol in MASLD that includes retatrutide (not a dedicated retatrutide-only liver trial), building on the Phase 2 liver fat sub-study TRANSCEND Program -- Type 2 Diabetes TRANSCEND Phase 3 program evaluating retatrutide specifically for type 2 diabetes

10.1016/j.phrs.2019.104559 90 XiaoH.SunX.LinZ.YangY.ZhangM.XuZ.et al (2022)

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The abstract does not include the specifics for these endpoints, only stating that there were significant improvements. Eli Lilly previously disclosed in a press release, that they expected patients using tirzepatide to lose between 18-20% of their body weight