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Adverse Reactions (6.1).] Maintenance of JANUVIA During Initiation and Titration of Insulin Glargine A total of 746 patients with type 2 diabetes (mean baseline HbA1C 8.8%, disease duration 10.8 years) participated in a 30-week, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of continuing JANUVIA during the initiation and uptitration of insulin glargine

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However, the direct impact of SASP on vascular cells remains underexplored, with potential mechanisms possibly involving the propagation of senescence or amplification of localized inflammation