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Glutathione is unique because it is "recyclable." After it neutralizes a free radical, it becomes oxidized

Side effects are mainly seen with IV glutathione and include potential damage to kidneys, liver & thyroid

A total of 200 mg/kg of GSH (available in Japan as Tathion, Yamanouchi Pharmaceutical, Tokyo, Japan) was administered intra-venously to 10 patients before cardiopulmonary bypass surgery, and the influence on postoperative renal dysfunction was compared with 9 other patients undergoing the same procedure without GSH administration

This finding may reflect a weaker antioxidant defense system in the ACC in males