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Future research should integrate genomics, metabolomics, and microbiomics to develop biomarker-based personalized dietary intervention protocols, thereby enhancing therapeutic efficacy while reducing potential risks (Table 1)

Sadri responded to FDA's Form 483 to explain the discrepancies, including delayed activation of the clinical trial site and shortening of the enrollment period, and said he would update the standard operating procedures

Obesity not only strains vital organs but also impairs mobility and energy levels, making daily activities more challenging

Tirzepatide follows a structured dose-escalation schedule, starting at 2.5 mg once weekly and increasing every 4 weeks (to 5 mg, 7.5 mg, 10 mg, 12.5 mg, and up to 15 mg) for both Mounjaro and Zepbound