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Carnitine has been supplemented in a great variety of patients, such as inborn errors in the carnitine system, mitochondrial beta oxidation, mitochondrial acyl-CoA-linked enzymes, oxidative phosphorylation [35,84], in cardiovascular diseases [85], AIDS [60], in diabetes mellitus [86], chronic fatigue syndrome [87], chemotherapy- [88] and interferon-a- [89] induced fatigue, children with ADHD [90]