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Description

They bind to complementary sequences on target mRNAs, resulting in negative regulation through degraded target mRNA or repressed the translation (Beermann et al., 2016)

Therefore, we chemically synthesized the relevant macrocycles with C-terminal (-alanine) 2 -FLAG tags (A 2 -FLAG), with the resulting peptides referred to as aML5-FLAG, aMD4-FLAG and aMD5-FLAG (Supplementary Table 2 and Supplementary Fig