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FA (5 mg mL 1 , dissolved in 0.5 M NaHCO 3 , at pH 8) was added and stirred overnight

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Complementing these classical antioxidant systems, cancer cells also exploit radical-trapping antioxidant mechanisms mediated by FSP1 and GCH1, both of which are frequently upregulated in diverse malignancies and markedly contribute to ferroptosis resistance (21,139)

Regarding the effect of fat on GLP-1 concentration, diets enriched in monounsaturated fatty acids (MUFA) induce higher GLP-1 concentrations with a positive effect on glycemic control.78 However, previous study did not find the same effect.79 The postprandial GLP-1 response to intraluminal fats may also depend on the chain length of fatty acids