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& Viles, J

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Subgroup analyses based on various demographic and disease characteristics at baseline were specified a priori for PIONEER 6 and randomization was stratified by CV disease or risk factors at baseline

10 Esta reduccin en el plasma se debe a que la sntesis endgena se ve alterada durante la hemodilisis, as como a la deficiencia de algunos cofactores (vitamina B6, niacina, vitamina C y hierro) que son necesarios en la ruta enzimtica encargada de sintetizar carnitina