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Hum Pathol 2015

A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation

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corpus callosum in CAE), in the former, a deliberately orchestrated primary autoimmune process directed at myelin antigens results in lymphocytic infiltration, secondary injury to white matter and a universal innate response, whereas in CAE, where the primary insult is a biochemical one deliberately targeting intrinsic CNS myelin, following immune stimulation, the resulting lesion is pathologically similar (Day, 2005