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As such, they caution the use of L-carnitine supplements, especially for individuals at high cardiovascular risk, such as those with metabolic syndrome

Introduction The concept of the leaky gut has received increasing attention in the lay press and also in the scientific literature of late due to its associations with numerous gastrointestinal (GI) and non-GI diseases such as irritable bowel syndrome, Alzheimers disease, asthma, type 2 diabetes, hepatic steatosis, and many others [1] to the point that dietary modifications, probiotics, and other interventions intended to increase gut integrity are recommended as treatments for a host of diseases [2, 3]

Disease-modifying antirheumatic drugs (DMARDs) like methotrexate can slow autoimmune progression when started within 6 months of symptom onset, significantly improving long-term outcomes

For weight management, semaglutide (Wegovy) and liraglutide (Saxenda) are licensed