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Dubnov S, Bennett ER, Yayon N, Yakov O, Bennett DA, Seshadri S, Mufson E, Tzur Y, Greenberg D, Kuro-o M, Paldor I, Abraham CR, Soreq H (2024) Knockout of the longevity gene Klotho perturbs aging and Alzheimers disease-linked brain microRNAs and tRNA fragments

However, science is particularly interested in it because of its many physiological, endocrine and modulatory effects, such as its ability to alter corticotropin levels, inhibit somatostatin secretion, normalize blood pressure, reduce stress, influence sleep rhythms, or chronic pain perception

They improve insulin sensitivity, regulate appetite and increase satiety

Trail runs around San Tan Mountain Regional Park, weekends at Schnepf Farms, golf at Encanterra, youth sports tournaments, and long days outside in summer heat that regularly tops 110F