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Compared with nonusers, adults taking GLP-1s had a: 17 percent lower risk of venous thromboembolism, or blood clots in the veins 31 percent lower risk of pulmonary embolism, a potentially life-threatening clot that travels to the lungs 21 percent lower risk of going to the emergency department 44 percent lower risk of all-cause mortality (death from any cause) Researchers also observed lower stroke rates among GLP-1 users, although this difference didnt reach statistical significance

The use of GLP-1RAs was prohibited until after the follow-up visit, 5 weeks after the last dose of trial product

Administering doses higher than natural levels may increase the risk of mortality