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High lipid (fat) levels in the blood

On the immune side, obesity may cause M2 macrophages ferroptosis due to damage to iron-rich ATMs (MFe hi ) and antioxidant ATMs (Mox), and lead to Treg cells ferroptosis through reductions in NRF2, GPX4, and GCH1 levels

Autoimmune conditions: May require lower starting doses and immune-first strategies Multiple injuries: Sequencing may matter more than stacking everything at once Complex medication regimens: Interaction review is essential Severe deconditioning: Foundational rehab may need to precede peptides These cases highlight why clinician guidance matters

Meticulous clinical oversight is vital for safety and long-term efficacy