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Description

Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]

Moreover, the faster metabolic rate of short-acting GLP-1RAs may induce abrupt changes in gastrointestinal function, further supporting the higher incidence of nausea and vomiting with these agents