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Hyperbilirubinemia develps because of one of three possible causes: (1) excessive hemolysis of red blood cells (RBC) (also known as prehepatic icterus)high bilirubin in the blood stream occurs because of an overload of the mononuclear/phagocyte system with heme pigments from RBC destruction, (2) hepatic parenchymal disease or insufficiency (also known as hepatic icterus)resulting in lack of normal bilirubin metabolism in hepatocytes and regurgitation of the pigments into the blood stream when they are not taken up into cells and excreted in bile, and (3) disease of gall bladder, biliary tract, or pancreatic duct (also known as posthepatic icterus)resulting in obstruction of the bile ducts or loss of bile into the abdomen (duct or gall bladder rupture and bile peritonitis)

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Type 2 diabetes mellitus most often develops due to disorders of carbohydrate metabolism

With the patent expiry of Semaglutide in India, we are witnessing a historic moment in medicine accessibility