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We observed 1-year mortality in patients with type 2 diabetes who were prescribed GLP1-RAs to be substantially lower than patients not prescribed GLP1-RAs with a disproportionate benefit observed in those also diagnosed with OSA, says Cosmo Fowler, MD, lead researcher and CHEST 2025 presenter, in a release

Cited 2/7/17 McCulloch DK (2016b): Thiazolidinediones in the treatment of diabetes mellitus

Alternatively, alpha-MSH (the endogenous ligand) shows modest MC1R preference but has a plasma half-life under 10 minutes, requiring continuous infusion in cellular models