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A new study published in JAMA Internal Medicine examines the safety of glucagon-like peptide 1 (GLP-1) receptor agonists, along with other second-line medications used in managing diabetes in early pregnancy

We have learned that many of the GLP-1 benefits in humans are also weight-loss independent, which is fascinating. Even albiglutide (Tanzeum, GlaxoSmithKline), which was taken off the market because it wasnt as good as other GLP-1s at reducing glucose and weight, reduced risk for major adverse cardiovascular events (MACE) by 22% compared with placebo despite no difference between the groups in weight loss, he said

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