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The results of a trial of semaglutide in obese patients with HFpEF showed a significant amelioration of symptoms and improvements in motor function and weight loss compared with patients treated with a placebo

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Severe reactions (and should be seen immediately in the doctors office or Emergency Department) include seizures, lethargy (and unable to be woken), wheezing, hives, dizziness, swelling of the throat, fainting or rapid heartbeat

Factors providers may review include: BMI medications weight-related conditions treatment goals previous weight loss history Patients should complete a medical assessment before beginning treatment