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At 13 months, they projected a relative BMI change from baseline of 0.4% with lifestyle counselling, 4.3% with liraglutide, 4.8% with mid-dose phentermine and topiramate, 7.1% with top-dose phentermine and topiramate, and 13.3% with semaglutide

[DOI] [PubMed] [Google Scholar] 27.Andreadis P., Karagiannis T., Malandris K., Avgerinos I., Liakos A., Manolopoulos A., Beklari E., Matthews D.R., Tsapas A

In ATTAIN-1, 3,127 overweight participants without diabetes were enrolled, while in ATTAIN-2, 1,613 overweight patients with type 2 diabetes were enrolled

Most patients will get some vitamin B12 in their daily multivitamin, however, many will require additional supplementation in the form of a pill or a longer-lasting injection