Tirzepatide continues expanding its indications
For patients in active weight loss or GLP-1 programs, adequate B12 supports red blood cell formation, oxygen delivery, and energy production, which makes it easier to maintain movement, preserve lean mass, and engage with the plan instead of slipping into exhaustion
One study revealed that psyllium husk resulted in reduced body weight, blood sugar levels, constipation, and cholesterol
Taken together, disruptions in short-chain fatty acid-related metabolism, gut-derived inflammation, bile acid signaling, and ammonia/nitrogen handling support a mechanistic contribution of the gut-liver axis to HE ( Fig