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Other substituents: modifications can fine-tune potency and selectivity, potentially reducing off-target activity

Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Morgan A, Sarwal MM, Pasricha PJ, Butte AJ: Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease

Tirzepatide works by: Stimulating the release of insulin, a hormone that helps regulate blood sugar levels Slowing the release of glucose from the stomach into the small intestine Reducing appetite and increasing feelings of fullness Increasing the bodys sensitivity to insulin, making it easier for glucose to enter cells Tirzepatide is administered through a once-weekly injection and is available under the brand names Mounjaro and Zepbound

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