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Vitamin B12 deficiency symptoms Common symptoms of vitamin B12 deficiency include: Tiredness

Gln depletion therapy can inhibit Gln metabolism in tumor cells, but in colon cancer, it has been observed that Gln depletion promotes the expression of the aspartate/glutamate transporter SLC1A3 in tumor cells, increasing the intracellular glutamate concentration and promotes Gln synthesis

The compound is classified as an amylin receptor agonist with demonstrated activity at calcitonin receptor (CTR) and receptor activity-modifying protein (RAMP) complexes, particularly CTR/RAMP1, CTR/RAMP2, and CTR/RAMP3 heterodimers

Data are from n = 68 biologically independent oxidized cysteine reactivity profiling experiments and n = 3 biologically unenriched proteomics experiments