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Chugai and Lilly published the preclinical pharmacology data of this molecule together, and Lilly is running Phase III studies on orforglipron for the treatment of Type 2 diabetes and for weight management in adults with obesity or overweight with at least one weight-related medical problem

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[20] [21] Patients should report any symptoms such as a lump in the neck, hoarseness, or difficulty swallowing Hypersensitivity reactions : Rare cases of serious allergic reactions have been reported Hypoglycaemia risk is generally low with GLP-1 monotherapy due to the glucose-dependent mechanism of action