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Importantly, these medications carry a boxed warning and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Multiple anti-inflammatory peptides target these specific cytokines

Its established role within peptide research has resulted in extensive investigation across numerous experimental models examining cellular signalling processes

Methods Study approval All the related experiments and protocols used in these studies were approved by the Ethical Committees of the University of Cordoba and Junta de Andalusia (Spain), according to EU normative for the use and care of experimental animals (EU Directive 2010/63/UE, September 2010)