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The American College of Cardiology/American Heart Association/The Obesity Society guidelines emphasize individualized treatment plans incorporating lifestyle modification, behavioral therapy, pharmacotherapy when appropriate, and metabolic/bariatric surgery for eligible patients

Important: never place your medication directly against an ice pack

The FDA has approved these agents based on extensive clinical trial data, but post-marketing surveillance continues to refine our understanding of their safety profile, including gastrointestinal and hepatobiliary effects

We analyzed the weekly incidence of side effects during the first two weeks that a participant recorded a given dose amount, using a Bayesian logistic mixed-effects model