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Diagnostic testing decisions depend on symptom patterns, clinical examination findings, and medical history

Published findings concerning body composition, glucose regulation, liver pathology and muscle function come from laboratory and animal studies rather than established human clinical trials

It has also been investigated in preclinical tests, where it has been found to elicit several beneficial effects: Altered metabolism: It prevents diet- and age-related obesity and insulin resistance

Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability