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In chronic venous leg ulcers (which often lack endogenous LL-37), topical treatment with synthetic LL-37 significantly accelerated healing rates compared to placebo [4]

Compounded medications may also provide additional benefits, such as adding vitamin B-12 or vitamin B-6 while compounding semaglutide for patients susceptible to B-12 or B-6 deficiency

At the top of the list: berberine, a plant compound dubbed natural semaglutide. Several Redditors report dropping more than 25 pounds in just weeks after adding berberine to their supplement stack, claiming that their results are comparable to prescription diabetes drugs like Ozempic and Metformin Berberine can be found over-the-counter at most health food and supplement stores for around $15 to $40 per bottle

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