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Notably, patients treated with PEG-Loxenatide accounted for the largest number in this study, but incidences of gastrointestinal adverse events (17.6% vs 30.6% to 51%) and hypoglycemia (3.1% vs 8.2% to 11.5%) were lower compared with those treated with other GLP-1RAs

TerryMWakemanKWilliamsBJMillerDMSakMAbdullaevZet alMalignant melanotic nerve sheath tumor with Prkar1a, Kmt2c, and gnaq mutations

Understanding these internal shifts is the main point, because they explain why shedding begins a few months after starting therapy and why most cases improve when the underlying stress is corrected