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Systematic review registration: 1 Introduction Cancer is currently one of the main social, economic, and publichealth challenges ( Latin America and the Caribbean (LAC) is a region comprising 49 countries and territories (the term territories groups overseas and unincorporated areas) and can be subdivided into three subregions based on geographic location: Central America (8 countries), South America (12 countries and 1 territory), and the Caribbean (13 countries and 15 territories)

Promotes Healthy Lipid Levels: IGF-1 has been shown to positively affect cholesterol levels, aiding in maintaining cardiovascular health, particularly important for women as they approach mid-life and beyond

Known as the incretin effect, GLP-1 and its synergetic sister hormone glucose-dependent insulinotropic polypeptide (GIP), are rapidly released by lower enteroendocrine L-cells (GLP-1) or upper enteroendocrine K-cells (GIP) in the gut following food intake and rising circulatory glucose levels to augment the glucose-stimulated release of insulin by pancreatic cells