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Small molecules like aspirin or ibuprofen can tolerate significant temperature swings with minimal impact on potency

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These patients also had cardiovascular disease, but didnt have diabetes (the condition semaglutide is primarily used for), and early on in the study, their MACE risk decreased regardless of how much weight they lost or their waist circumference

Notably, the expression of GLP1 receptor has been detected within all four chambers of the heart, sinoatrial node and arteriole smooth muscle cells (Baggio et al., 2018