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These data indicate that GSH depletion is directly responsible for the observed induction of NRF2 activity in Gclc L-KO mice

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GHK-Cu has one of the most extensively studied gene expression profiles of any peptide compound microarray studies by Pickart and colleagues identified that GHK-Cu modulates over 4,000 human genes, including upregulation of tissue repair genes and downregulation of inflammatory and cancer-associated pathways

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On the antioxidant side, Vitamin C and glutathione have a "recycling" relationship

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