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An important origin of ROS within erythrocytes is the autoxidation of hemoglobin, generating superoxide radicals (Cimen, 2008)

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The data revealed that patients taking greater than 600 mg/day of NAC reported a 45.8% significant positive effect on their symptoms, while direct glutathione administration yielded a 42.4% significant positive response rate, highlighting the critical importance of the redox pathway in symptom management

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