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It was also observed that in the retina, HAT p300-mediated acetylation is associated with proinflammatory molecule induction, suggesting that transcriptional co-activator-mediated acetylation is a major contributor of diabetic retinopathy 334

Decreased stomach acid production also provides an environment conducive to the overgrowth of anaerobic bacteria in the stomach, which further interferes with vitamin B 12 absorption (3)