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Notably, in SURMOUNT-1, lean mass loss as a proportion of total mass lost was similar (~25%) across the treatment and placebo groups 62 , and in the treatment group, physical function scores were improved relative to baseline and by comparison to the placebo group at the end of the study 62, 63

B12 supplements can greatly improve health, which is important for those with thalassemia at risk of deficiency

They can help you weigh the theoretical risks against the benefits in your specific situation

The full description of each category should be read on the FDAs website, but in short, materials listed in Category 1 may be used as bulk drug substances provided that all other relevant legal and regulatory conditions are met