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PubMed Yang, L., Wang, Y., Dong, X., Chen, Y., Li, X., Li, L., Zheng, C., Cao, C., Zhang, H., Huang, W., Zhang, C., Yang, D., Zhao, Q., Wu, B., & Shen, D.D

Weight loss medication may not be right for everyone, and it's best to carefully review your medical history to determine if a GLP-1 injectable will be safe and effective for you to take

For example, four pens of a GLP-1 medication may cost around \$650 with a manufacturer coupon, lasting about 34 months at standard dosages

Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)