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These medications were originally created to help with blood sugar management in people with diabetes, Ali says

Source: Valko, M., Rhodes, C

27 Importantly, GLP-1 action is short-lived, with a half-life of just 12 minutes in the bloodstream under normal physiological conditions, after which it is broken down by the enzyme dipeptidyl peptidase IV (DPP-4), resulting in a loss of its biological activity