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Description

This makes it structurally distinct from dual-receptor compounds like Tirzepatide and single-receptor compounds like Semaglutide

For patients with obesity-related comorbidities such as hypertension, dyslipidaemia, or fatty liver disease these combined effects could represent a clinically meaningful advance if confirmed in Phase 3 data

Ex-4 also reverses the high-fat-diet-induced impairment of brain-derived neurotrophic factor (BDNF) signaling and the inflammatory response in the 3xTg-AD mouse model [76]