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In the maintenance phase, the frequency is typically reduced significantly

In some cases, if the rapid strep test result is negative but symptoms strongly suggest infection, a throat culture may be sent to a lab for confirmation, which can take 24 to 48 hours

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Given the limited therapeutic benefits associated with NAC in cancer treatment, and the number of other antioxidants shown above to help reduce the toxicities of these two chemotherapeutic agents, there appears little reason to consider NAC a first-line adjunct with either agent